In 2025, 130 US girls were named Serene, making it the 1,609th most common girls’ name of the year, up 97 places from #1,706 in 2024. That is 10 more than the 120 girls named Serene in 2024. Its best rank for girls was #1,609, reached in this year, 2025. That year also had the most girls given the name: 130. For comparison, it was #2,551 in 2015 and #5,204 in 1950.
Social Security card records list Serene in 95 years of the 146 from 1880 to 2025, starting in 1914 with 5 babies. In all, 3,226 US babies have been given the name, all of them girls. Its busiest decade was the 2010s, with 800 babies named Serene.
Over the 10 years from 2016 to 2025, 988 US girls were named Serene; the busiest of those years was 2025, with 130. In 2025 that was about 1 in 12,364 of the girls in SSA’s list for the year.
Among the states, Serene ranked highest in Maryland in 2025, at #825 for girls there. It was not in the top 100 of any state. Related spellings in the SSA files include Seren (1,081 babies since 1880). Rarer spellings such as Sereen, Cyrene and Siren are summarised on this page.